2010-03-26	Colorado Rapids	(H)	0	- 1	L
2010-04-01	Los Angeles Galaxy	(A)	0	- 2	L
2010-04-10	New York Red Bulls	(H)	2	- 0	W
2010-04-17	Houston Dynamo	(A)	0	- 3	L
2010-04-24	San Jose Earthquakes	(H)	3	- 2	W
2010-05-01	Chicago Fire SC	(A)	1	- 1	D
2010-05-05	New England Revolution	(A)	4	- 0	W
2010-05-08	Houston Dynamo	(H)	0	- 2	L
2010-05-15	Columbus Crew	(A)	0	- 1	L
2010-05-22	Real Salt Lake	(H)	1	- 2	L
2010-05-29	D.C. United	(A)	2	- 3	L
2010-06-05	New York Red Bulls	(A)	0	- 1	L
2010-06-26	FC Dallas	(H)	1	- 2	L
2010-07-03	Philadelphia Union	(H)	1	- 1	D
2010-07-10	Sporting Kansas City	(A)	2	- 0	W
2010-07-24	Real Salt Lake	(A)	1	- 1	D
2010-07-31	Columbus Crew	(H)	3	- 1	W
2010-08-07	Toronto FC	(A)	1	- 2	L
2010-08-14	Seattle Sounders FC	(H)	0	- 0	D
2010-08-21	FC Dallas	(A)	0	- 1	L
2010-08-29	D.C. United	(H)	1	- 0	W
2010-09-04	Colorado Rapids	(A)	0	- 3	L
2010-09-11	New England Revolution	(H)	2	- 0	W
2010-09-19	Sporting Kansas City	(H)	0	- 2	L
2010-09-25	Philadelphia Union	(A)	0	- 3	L
2010-10-03	Los Angeles Galaxy	(H)	1	- 2	L
2010-10-09	Toronto FC	(H)	3	- 0	W
2010-10-15	Seattle Sounders FC	(A)	1	- 2	L
2010-10-21	San Jose Earthquakes	(A)	0	- 3	L
2010-10-24	Chicago Fire SC	(H)	1	- 4	L