2010-11-21	Academia Chişinău	- Dinamo-2 Bender		-
2010-11-21	RS Lilcora FC	- FC Olimp Ungheni	3	- 1
2010-11-21	Speranţa Crihana Veche	- CS Mipan-Voran	3	- 1
2010-11-21	CF Locomotiv Bălţi	- CF Intersport-Aroma	0	- 0
2010-11-21	FC Olimpia-2 Bălţi	- FC Cahul-2005	0	- 4
2010-11-21	FC Sheriff-2 Tiraspol	- FC Sfîntul Gheorghe-2	0	- 0
2010-11-21	FC Milsami-Ursidos-2	- FC Zimbru-2 Chişinău	2	- 0
2010-11-21	CSCA-Rapid-2 Chişinău	- FC Dinamo-Auto	2	- 1